Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
istB4Insertion sequence IS21 ATP-binding protein; Function of strongly homologous gene; extrachromosomal origin. (263 aa)    
Predicted Functional Partners:
NIDE2837
Putative Transposase for insertion sequence element IS21; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.
   0.956
NIDE0583
Conserved membrane protein of unknown function, UPF0114; Homologs of previously reported genes of unknown function.
 
      0.879
istA-2
Putative Transposase for insertion sequence element IS21; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.
   0.808
istA
Transposase for insertion sequence element IS21; Function of strongly homologous gene; enzyme.
   0.808
NIDE2138
Putative Transposase for insertion sequence element IS21; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.
   0.808
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 
 0.742
dnaB-2
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 
 0.742
NIDE2840
Putative Reverse transcriptase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.
 
     0.610
NIDE2834
Transposase (N-terminal fragment); Function of strongly homologous gene; enzyme.
       0.565
NIDE2835
Transposase (C-terminal fragment); Function of strongly homologous gene; extrachromosomal origin.
       0.565
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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