close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2933Putative P-loop guanosine triphosphatase, CobW-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (315 aa)    
Predicted Functional Partners:
map
Methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
    
 
 0.817
rpsN
30S ribosomal protein S14; Function of homologous gene experimentally demonstrated in an other organism; structure.
  
 
 0.814
NIDE0385
Putative Manganese transport system, periplasmic binding component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein; Belongs to the bacterial solute-binding protein 9 family.
  
  
 0.784
rpmB
50S ribosomal protein L28; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.756
NIDE0281
Putative RNA polymerase-binding protein DksA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
  
  
 0.608
dksA
DnaK suppressor protein (modular protein); Function of homologous gene experimentally demonstrated in an other organism; regulator.
  
  
 0.608
NIDE3409
Protein of unknown function, putative RNA polymerase-binding protein DksA; No homology to any previously reported sequences; 11160083, 12665246, 15294156, 15294157, 15568992, 15718139, 15899978, 15963892, 17210253, 2180916.
  
  
 0.608
rpmG
50S ribosomal protein L33; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL33 family.
  
  
 0.593
NIDE2932
Membrane protein of unknown function; No homology to any previously reported sequences; 2687240.
       0.543
cobL
Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.527
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (20%) [HD]