Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
Experiments
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[Homology]
Score
NIDE2953Protein of unknown function, Phospholipase D-like; No homology to any previously reported sequences; 8732763, 8755242. (752 aa)    
Predicted Functional Partners:
NIDE2954
Protein of unknown function; No homology to any previously reported sequences; 7684291.
       0.773
NIDE0081
Homologs of previously reported genes of unknown function.
    
 0.504
NIDE0273
Conserved protein of unknown function, small GTP-binding protein; Homologs of previously reported genes of unknown function; 11099382, 12163169, 12384139, 12728271, 17143896.
    
 0.504
NIDE2952
Exported protein of unknown function; No homology to any previously reported sequences.
       0.475
NIDE1587
Protein of unknown function, putative Sensory histidine kinase with methyltransferase region; No homology to any previously reported sequences; 11369279, 11489844, 15009198, 16176121, 16622408, 18076326, 7699720, 9301332, 9382818.
   
 
 0.474
NIDE2940
Homologs of previously reported genes of unknown function.
  
    0.429
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.415
NIDE2955
Protein of unknown function; No homology to any previously reported sequences.
       0.411
NIDE2956
Protein of unknown function; No homology to any previously reported sequences; 2687240, 7684291.
       0.411
NIDE1185
Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.409
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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