Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2982Homologs of previously reported genes of unknown function. (270 aa)    
Predicted Functional Partners:
manB/pgm
Bifunctional Phosphoglucomutase/Phosphomannomutase; Function of strongly homologous gene; enzyme.
  
  
 0.820
manC/pmi
Bifunctional Mannose-1-phosphate guanylyltransferase/Mannose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
  
 0.810
kdsC
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
    0.650
NIDE2867
Putative Glycosyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.606
NIDE2986
Putative Undecaprenyl-phosphate glucose phosphotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.596
fbp-2
Fructose-1-6-bisphosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FBPase class 1 family.
     
 0.590
NIDE0890
Putative Lipopolysaccharide biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
    0.478
fbaB
Fructose-bisphosphate aldolase class I; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.468
degQ
Protease DegQ; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.434
NIDE3119
Conserved protein of unknown function, Beta-lactamase-like; Homologs of previously reported genes of unknown function; 11916693.
  
    0.410
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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