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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kdsC3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (153 aa)    
Predicted Functional Partners:
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family.
  
 0.998
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
  
 0.997
kdsD
Arabinose-5-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the SIS family. GutQ/KpsF subfamily.
  
 0.989
neuA
N-acylneuraminate cytidylyltransferase; Function of strongly homologous gene; enzyme.
 
   0.964
NIDE2999
Putative N-acetylneuraminate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 0.962
manC/pmi
Bifunctional Mannose-1-phosphate guanylyltransferase/Mannose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the mannose-6-phosphate isomerase type 2 family.
      0.721
rfaEb
D-beta-D-heptose 1-phosphate adenosyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
      0.698
manB/pgm
Bifunctional Phosphoglucomutase/Phosphomannomutase; Function of strongly homologous gene; enzyme.
       0.663
NIDE2982
Homologs of previously reported genes of unknown function.
  
    0.654
fbp-2
Fructose-1-6-bisphosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FBPase class 1 family.
  
    0.553
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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