Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
wecB-2UDP-N-acetylglucosamine 2-epimerase; Function of strongly homologous gene; enzyme. (383 aa)    
Predicted Functional Partners:
NIDE2999
Putative N-acetylneuraminate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.988
neuA
N-acylneuraminate cytidylyltransferase; Function of strongly homologous gene; enzyme.
  
 0.980
NIDE2831
UDP-glucose/GDP-mannose dehydrogenase family protein; Function of strongly homologous gene; enzyme; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
  
 0.793
NIDE2997
Putative UDP-glucose 4-epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.790
NIDE3001
Protein of unknown function; No homology to any previously reported sequences.
       0.773
NIDE2996
Homologs of previously reported genes of unknown function.
 
     0.745
NIDE3002
Protein of unknown function; No homology to any previously reported sequences.
       0.727
NIDE3003
Protein of unknown function, putative O-methyltransferase; No homology to any previously reported sequences.
       0.726
NIDE3007
Membrane protein of unknown function, putative polysaccharide biosynthesis protein; No homology to any previously reported sequences; 8226646.
  
  
 0.694
NIDE2689
Conserved protein of unknown function, putative Hexapeptide repeat transferase; Homologs of previously reported genes of unknown function; 7481807, 8293817.
 
  
 0.631
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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