Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rfbAGlucose-1-phosphate thymidylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (244 aa)    
Predicted Functional Partners:
rfbD
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
  
 0.999
rfbB-2
dTDP-glucose 4,6-dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
 0.999
rfbC
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
 0.994
udg
UDP-glucose 6-dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.967
udg-2
UDP-glucose 6-dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.967
NIDE4374
Putative dTDP-4-dehydrorhamnose reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.954
rfbF
Glucose-1-phosphate cytidylyltransferase; Function of strongly homologous gene; enzyme.
  
 
0.939
galU
UTP--glucose-1-phosphate uridylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
0.937
manB/pgm
Bifunctional Phosphoglucomutase/Phosphomannomutase; Function of strongly homologous gene; enzyme.
  
 
 0.923
NIDE2334
Protein of unknown function, putative Glycosyl transferase; No homology to any previously reported sequences; 9334165.
 
  
 0.922
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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