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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE3049Conserved protein of unknown function, contains HD domain; Homologs of previously reported genes of unknown function. (473 aa)    
Predicted Functional Partners:
NIDE3048
Homologs of previously reported genes of unknown function.
       0.776
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.725
lon-2
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
       0.724
galU
UTP--glucose-1-phosphate uridylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.512
NIDE3308
Homologs of previously reported genes of unknown function.
  
     0.440
NIDE3052
Putative Hybrid sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
       0.434
NIDE3050
Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.433
NIDE3051
CheY-like response regulator; Function of strongly homologous gene; regulator.
       0.433
NIDE3042
Putative Outer membrane chaperone Skp precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
 
     0.408
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.