| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NIDE3062 | NIDE3063 | NIDE3062 | NIDE3063 | Protein of unknown function; No homology to any previously reported sequences. | Putative DNA polymerase IV, family X (N-terminal fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.567 |
| NIDE3062 | thiE2 | NIDE3062 | NIDE3059 | Protein of unknown function; No homology to any previously reported sequences. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.449 |
| NIDE3062 | thiG | NIDE3062 | NIDE3060 | Protein of unknown function; No homology to any previously reported sequences. | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.693 |
| NIDE3062 | thiS | NIDE3062 | NIDE3061 | Protein of unknown function; No homology to any previously reported sequences. | Thiamine biosynthesis protein ThiS; Function of strongly homologous gene; carrier. | 0.693 |
| NIDE3063 | NIDE3062 | NIDE3063 | NIDE3062 | Putative DNA polymerase IV, family X (N-terminal fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Protein of unknown function; No homology to any previously reported sequences. | 0.567 |
| NIDE3063 | thiE2 | NIDE3063 | NIDE3059 | Putative DNA polymerase IV, family X (N-terminal fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.454 |
| NIDE3063 | thiG | NIDE3063 | NIDE3060 | Putative DNA polymerase IV, family X (N-terminal fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.612 |
| NIDE3063 | thiS | NIDE3063 | NIDE3061 | Putative DNA polymerase IV, family X (N-terminal fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Thiamine biosynthesis protein ThiS; Function of strongly homologous gene; carrier. | 0.614 |
| thiE2 | NIDE3062 | NIDE3059 | NIDE3062 | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | Protein of unknown function; No homology to any previously reported sequences. | 0.449 |
| thiE2 | NIDE3063 | NIDE3059 | NIDE3063 | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | Putative DNA polymerase IV, family X (N-terminal fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.454 |
| thiE2 | thiG | NIDE3059 | NIDE3060 | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.965 |
| thiE2 | thiS | NIDE3059 | NIDE3061 | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | Thiamine biosynthesis protein ThiS; Function of strongly homologous gene; carrier. | 0.883 |
| thiG | NIDE3062 | NIDE3060 | NIDE3062 | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | Protein of unknown function; No homology to any previously reported sequences. | 0.693 |
| thiG | NIDE3063 | NIDE3060 | NIDE3063 | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | Putative DNA polymerase IV, family X (N-terminal fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.612 |
| thiG | thiE2 | NIDE3060 | NIDE3059 | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.965 |
| thiG | thiS | NIDE3060 | NIDE3061 | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | Thiamine biosynthesis protein ThiS; Function of strongly homologous gene; carrier. | 0.996 |
| thiS | NIDE3062 | NIDE3061 | NIDE3062 | Thiamine biosynthesis protein ThiS; Function of strongly homologous gene; carrier. | Protein of unknown function; No homology to any previously reported sequences. | 0.693 |
| thiS | NIDE3063 | NIDE3061 | NIDE3063 | Thiamine biosynthesis protein ThiS; Function of strongly homologous gene; carrier. | Putative DNA polymerase IV, family X (N-terminal fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.614 |
| thiS | thiE2 | NIDE3061 | NIDE3059 | Thiamine biosynthesis protein ThiS; Function of strongly homologous gene; carrier. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.883 |
| thiS | thiG | NIDE3061 | NIDE3060 | Thiamine biosynthesis protein ThiS; Function of strongly homologous gene; carrier. | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.996 |