Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
NIDE3068Conserved protein of unknown function, UPF0102; Homologs of previously reported genes of unknown function; Belongs to the UPF0102 family. (128 aa)    
Predicted Functional Partners:
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.797
yifB
Putative ATP-dependent protease, Mg chelatase-related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
  
 0.796
NIDE1089
Putative Phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
    0.730
NIDE3065
Putative Murein hydrolase EnvC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process.
 
    0.713
smf
Protein SMF, putative DNA protecting protein DprA; Function of strongly homologous gene; phenotype.
 
  
 0.694
trmD
tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
 
     0.692
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
   0.677
rimM
Ribosome maturation factor RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
       0.649
ftsE
Cell division protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
     
 0.642
NIDE3066
Putative Cell division protein FtsX; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
       0.627
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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