Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ybbOOxidoreductase, Glucose/ribitol dehydrogenase family; Function of strongly homologous gene; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (287 aa)    
Predicted Functional Partners:
fabG4
3-oxoacyl-(acyl-carrier-protein) reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 
 0.698
NIDE3093
NUDIX hydrolase-family protein; Function of strongly homologous gene; enzyme; Belongs to the Nudix hydrolase family.
       0.618
NIDE2131
Putative 3-oxoacyl-(acyl-carrier-protein) reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 
 0.615
NIDE1742
Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.600
sucC
Succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
    
 0.594
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
      0.525
NIDE2152
Putative Polyketide synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.486
cyp
Cytochrome P450; Function of strongly homologous gene; enzyme; Belongs to the cytochrome P450 family.
 
 
 0.471
NIDE2150
Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 
 0.433
NIDE3330
Conserved protein of unknown function, SDR family; Homologs of previously reported genes of unknown function; 7742302.
 
 
 
 0.423
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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