Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fadDLong-chain-fatty-acid--CoA ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (571 aa)    
Predicted Functional Partners:
NIDE2152
Putative Polyketide synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 0.976
NIDE3128
Putative 2-succinylbenzoate--CoA ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 
0.940
NIDE2151
Putative Non-ribosomal peptide synthetase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
      0.895
aroA
3-phosphoshikimate-1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
      0.881
fadA
3-ketoacyl-CoA thiolase; Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 0.766
NIDE3106
Homologs of previously reported genes of unknown function; 7845226.
       0.701
NIDE3103
Putative 3-hydroxyacyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.683
NIDE3129
Putative Acyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.676
paaF
Putative Enoyl-CoA hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 
 0.658
NIDE1742
Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.647
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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