Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE3109Putative 4-hydroxyphenylpyruvate dioxygenase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (198 aa)    
Predicted Functional Partners:
NIDE3110
Putative Homogentisate 1,2-dioxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.957
pccB
Propionyl-CoA carboxylase; Function of strongly homologous gene; enzyme.
  
  
 0.822
NIDE3111
Putative Fumarylacetoacetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.815
scpAa
Methylmalonyl-CoA mutase (N-terminal fragment); Function of strongly homologous gene; enzyme.
 
   
 0.695
scpAb
Methylmalonyl-CoA mutase (C-terminal fragment); Function of strongly homologous gene; enzyme.
 
   
 0.685
NIDE3112
Putative Orotate phosphoribosyltransferase (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.650
argK
LAO/AO transport system ATPase (fragment); Function of strongly homologous gene; transporter.
 
     0.618
NIDE3113
Putative 2-oxoisovalerate dehydrogenase, alpha subunit (TPP-binding module); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.603
NIDE3114
Putative 2-oxoisovalerate dehydrogenase, beta subunit (Transketolase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.590
phhB
4a-hydroxytetrahydrobiopterin dehydratase; Function of strongly homologous gene; enzyme.
  
  
 0.524
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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