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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE3111Putative Fumarylacetoacetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (334 aa)    
Predicted Functional Partners:
NIDE3110
Putative Homogentisate 1,2-dioxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.981
NIDE3109
Putative 4-hydroxyphenylpyruvate dioxygenase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.836
NIDE3112
Putative Orotate phosphoribosyltransferase (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.789
NIDE3114
Putative 2-oxoisovalerate dehydrogenase, beta subunit (Transketolase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.713
putA
Bifunctional protein PutA; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family.
  
 
 0.702
NIDE3113
Putative 2-oxoisovalerate dehydrogenase, alpha subunit (TPP-binding module); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.697
atoB
Acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.582
prpC
2-methylcitrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family.
  
    0.577
pccB
Propionyl-CoA carboxylase; Function of strongly homologous gene; enzyme.
 
  
 0.567
paaH
3-hydroxybutyryl-CoA dehydrogenase; Function of strongly homologous gene; enzyme.
  
  
 0.564
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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