Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE3111Putative Fumarylacetoacetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (334 aa)    
Predicted Functional Partners:
NIDE3110
Putative Homogentisate 1,2-dioxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.980
NIDE3109
Putative 4-hydroxyphenylpyruvate dioxygenase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.815
NIDE3112
Putative Orotate phosphoribosyltransferase (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.788
NIDE3114
Putative 2-oxoisovalerate dehydrogenase, beta subunit (Transketolase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.707
NIDE3113
Putative 2-oxoisovalerate dehydrogenase, alpha subunit (TPP-binding module); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.696
pccB
Propionyl-CoA carboxylase; Function of strongly homologous gene; enzyme.
 
  
 0.564
atoB
Acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 0.554
NIDE3115
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
   0.552
NIDE1157
Putative Imidazolonepropionase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     0.546
mvaB
Hydroxymethylglutaryl-CoA lyase; Function of strongly homologous gene; enzyme.
 
    0.542
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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