Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE3119Conserved protein of unknown function, Beta-lactamase-like; Homologs of previously reported genes of unknown function; 11916693. (282 aa)    
Predicted Functional Partners:
pccB
Propionyl-CoA carboxylase; Function of strongly homologous gene; enzyme.
  
    0.783
scpAa
Methylmalonyl-CoA mutase (N-terminal fragment); Function of strongly homologous gene; enzyme.
       0.773
scpAb
Methylmalonyl-CoA mutase (C-terminal fragment); Function of strongly homologous gene; enzyme.
       0.773
paaH
3-hydroxybutyryl-CoA dehydrogenase; Function of strongly homologous gene; enzyme.
 
    0.726
accA
Acetyl-CoA carboxylase, carboxytransferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
      0.707
NIDE3122
Putative Enoyl-CoA hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.698
mvaB
Hydroxymethylglutaryl-CoA lyase; Function of strongly homologous gene; enzyme.
  
    0.686
argK
LAO/AO transport system ATPase (fragment); Function of strongly homologous gene; transporter.
       0.686
atoB
Acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 0.683
prpC
2-methylcitrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family.
 
     0.654
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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