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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE3178Putative ATPase, AAA family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (506 aa)    
Predicted Functional Partners:
pan
Proteasome-associated ATPase; Function of strongly homologous gene; enzyme; Belongs to the AAA ATPase family.
 
 
0.923
NIDE0955
Uncharacterized ATPase, AAA family; Function of strongly homologous gene; enzyme; Belongs to the AAA ATPase family.
 
  0.896
NIDE3222
Putative Deacetylase, histone deacetylase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 0.703
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.688
NIDE3177
Protein of unknown function, contains DnaJ domain; No homology to any previously reported sequences; 12454054, 15170475, 8016869, 9644977.
  
 0.624
NIDE0081
Homologs of previously reported genes of unknown function.
    
 0.461
NIDE0273
Conserved protein of unknown function, small GTP-binding protein; Homologs of previously reported genes of unknown function; 11099382, 12163169, 12384139, 12728271, 17143896.
    
 0.461
msbA
Lipid A export ATP-binding/permease protein MsbA; Function of homologous gene experimentally demonstrated in an other organism; transporter.
   
 0.423
msbA-2
Lipid A export ATP-binding/permease protein MsbA; Function of homologous gene experimentally demonstrated in an other organism; transporter.
   
 0.423
msbA-3
Lipid A export ATP-binding/permease protein MsbA; Function of homologous gene experimentally demonstrated in an other organism; transporter.
   
 0.423
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.