close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE3198Putative Outer membrane efflux protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (516 aa)    
Predicted Functional Partners:
NIDE3199
Homologs of previously reported genes of unknown function.
       0.819
NIDE3201
Homologs of previously reported genes of unknown function.
       0.598
NIDE3200
Putative Ribonuclease Z; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.594
NIDE3197
Exported protein of unknown function; No homology to any previously reported sequences.
       0.584
NIDE2719
Putative Secretion protein HlyD family precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
   0.566
NIDE3943
RND-type efflux transporter, membrane-fusion protein; Function of strongly homologous gene; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
   0.542
macA
Efflux transporter, RND family, MFP subunit, putative Macrolide-specific efflux protein; Function of strongly homologous gene; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
   0.539
NIDE2724
Conserved protein of unknown function, contains GAF domain; Homologs of previously reported genes of unknown function; 12271124, 15708973, 9433123.
  
   0.521
NIDE3202
Protein of unknown function; No homology to any previously reported sequences.
       0.521
NIDE3250
Putative Heavy metal efflux system, membrane fusion protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
   0.506
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.