Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
smbPMetal-binding protein SmbP; Function of homologous gene experimentally demonstrated in an other organism; factor. (118 aa)    
Predicted Functional Partners:
hlyD
Secretion protein HlyD; Function of strongly homologous gene; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
      
 0.795
gcvT
Aminomethyltransferase, glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
      
 0.776
msrB
Methionine sulfoxide reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.655
NIDE3220
Putative 3-mercaptopyruvate sulfurtransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.558
NIDE3218
Putative N-carbamoyl-D-amino acid hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.552
NIDE3221
Protein of unknown function, NrfA-like; No homology to any previously reported sequences; 10841552, 11929995, 11938352, 8039676, 8057835, 8816789, 9927663.
       0.498
NIDE3222
Putative Deacetylase, histone deacetylase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.498
gcvH
Glycine cleavage system, H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
      
 0.466
NIDE3217
Homologs of previously reported genes of unknown function; Belongs to the UPF0301 (AlgH) family.
       0.428
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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