Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
nifA-2Nif-specific regulatory protein NifA; Function of strongly homologous gene; regulator. (506 aa)    
Predicted Functional Partners:
NIDE0542
Protein of unknown function, putative Histidine kinase; No homology to any previously reported sequences.
   
 
 0.800
rpoN
RNA polymerase, sigma-54 (sigma N) factor; Function of homologous gene experimentally demonstrated in an other organism; factor.
 
   
 0.783
NIDE3570
Putative Hybrid sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 
 0.782
NIDE3593
Putative Hybrid sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 
 0.765
NIDE4240
Putative Hybrid sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 
 0.765
NIDE3462
Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 
 0.715
NIDE3941
Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 
 0.715
glnD
Putative (Protein-PII) uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
      
 0.642
glnB
Nitrogen regulatory protein PII; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family.
      
 0.631
glnB-2
Nitrogen regulatory protein P-II; Function of strongly homologous gene; regulator.
      
 0.631
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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