Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NIDE3250Putative Heavy metal efflux system, membrane fusion protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (410 aa)    
Predicted Functional Partners:
czcA-2
Heavy metal efflux pump, CzcA family; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
   0.968
NIDE3249
Putative Heavy metal efflux system, outer membrane lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
   0.953
czcA-3
Cation efflux system protein CzcA; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
   0.843
NIDE1804
Heavy metal efflux pump, CzcA family, putative Acriflavine resistance protein B; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
   0.837
czcA
Cation efflux system protein CzcA; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
   0.829
NIDE1767
Putative Cation efflux system protein CzcC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
   0.784
NIDE1802
Putative Outer membrane protein TolC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
   0.768
acrB
Acriflavin resistance protein acrB; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
   0.691
acrB2
RND-type permease AcrB; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
   0.689
NIDE2163
Putative Multidrug efflux transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
   0.651
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.