| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NIDE3291 | argS | NIDE3291 | NIDE3290 | Putative Glycosyl transferase, family 9; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Arginyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.640 |
| NIDE3291 | secD | NIDE3291 | NIDE3287 | Putative Glycosyl transferase, family 9; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.461 |
| NIDE3291 | secF | NIDE3291 | NIDE3286 | Putative Glycosyl transferase, family 9; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.429 |
| NIDE3291 | tgt | NIDE3291 | NIDE3289 | Putative Glycosyl transferase, family 9; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.598 |
| NIDE3291 | yajC | NIDE3291 | NIDE3288 | Putative Glycosyl transferase, family 9; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Preprotein translocase, subunit YajC; Function of homologous gene experimentally demonstrated in an other organism; membrane component. | 0.529 |
| argS | NIDE3291 | NIDE3290 | NIDE3291 | Arginyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative Glycosyl transferase, family 9; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.640 |
| argS | guaA | NIDE3290 | NIDE1422 | Arginyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.990 |
| argS | secD | NIDE3290 | NIDE3287 | Arginyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.675 |
| argS | secF | NIDE3290 | NIDE3286 | Arginyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.693 |
| argS | tgt | NIDE3290 | NIDE3289 | Arginyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.825 |
| argS | yajC | NIDE3290 | NIDE3288 | Arginyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Preprotein translocase, subunit YajC; Function of homologous gene experimentally demonstrated in an other organism; membrane component. | 0.777 |
| fbp | tgt | NIDE0321 | NIDE3289 | Peptidyl-prolyl cis-trans isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.650 |
| fkpA | tgt | NIDE3605 | NIDE3289 | Peptidylprolyl isomerase, FKBP-type; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.650 |
| guaA | argS | NIDE1422 | NIDE3290 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Arginyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.990 |
| guaA | queF | NIDE1422 | NIDE0820 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | NADPH-dependent 7-cyano-7-deazaguanine reductase (modular protein); Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.531 |
| guaA | tgt | NIDE1422 | NIDE3289 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.755 |
| guaA | yajC | NIDE1422 | NIDE3288 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Preprotein translocase, subunit YajC; Function of homologous gene experimentally demonstrated in an other organism; membrane component. | 0.476 |
| queA | queF | NIDE1010 | NIDE0820 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | NADPH-dependent 7-cyano-7-deazaguanine reductase (modular protein); Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.515 |
| queA | tgt | NIDE1010 | NIDE3289 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.993 |
| queF | guaA | NIDE0820 | NIDE1422 | NADPH-dependent 7-cyano-7-deazaguanine reductase (modular protein); Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.531 |
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