Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
moeAMolybdopterin biosynthesis protein MoeA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (432 aa)    
Predicted Functional Partners:
mobB
Molybdopterin-guanine dinucleotide biosynthesis protein B; Function of homologous gene experimentally demonstrated in an other organism; factor.
 
 0.994
NIDE3156
Putative Transcriptional regulator ModE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
 0.993
moaC
Molybdopterin cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
 0.989
moaB
Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.
 
 0.984
mobA
Putative Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
 0.981
moaE
Molybdopterin converting factor, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.972
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
 0.925
nuoG
NADH-quinone oxidoreductase, subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
 
   
 0.903
moeB
Molybdopterin biosynthesis protein MoeB; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.897
moaD
Molybdopterin converting factor, small subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.858
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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