Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
NIDE3347Homologs of previously reported genes of unknown function. (496 aa)    
Predicted Functional Partners:
NIDE3348
Putative Carbamoyltransferase, NodU family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.712
tadB
Pilus assembly protein TadB; Function of strongly homologous gene; transporter.
 
     0.531
tadC
Pilus assembly protein TadC; Function of strongly homologous gene; transporter.
 
     0.530
NIDE3349
Exported protein of unknown function; No homology to any previously reported sequences; 2058003, 2115931, 7553064.
       0.499
NIDE2113
Homologs of previously reported genes of unknown function.
 
     0.492
NIDE2112
Putative Pilus assembly ATPase CpaE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.453
cpaF
Pilus assembly ATPase CpaF; Function of strongly homologous gene; enzyme.
 
     0.429
NIDE1376
Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...]
 
     0.415
NIDE3346
Glycosyl transferase, family 2; Function of strongly homologous gene; enzyme.
  
     0.409
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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