STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
NIDE3352Putative Type IV pilus biogenesis/stability protein PilW; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. (233 aa)    
Predicted Functional Partners:
NIDE3351
Conserved protein of unknown function, putative Transcriptional regulator; Homologs of previously reported genes of unknown function; 15062080.
  
    0.828
NIDE3353
Putative Carbohydrate/purine kinase, PfkB family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.822
mtnP
Putative S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
       0.821
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
       0.801
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
       0.753
NIDE2108
Conserved protein of unknown function, TPR-like; Homologs of previously reported genes of unknown function; 10786835, 14659697, 7667876, 9482716.
  
     0.749
NIDE1061
Conserved protein of unknown function, contains TPR repeats; Homologs of previously reported genes of unknown function.
  
     0.748
NIDE3274
Protein of unknown function, contains TPR repeats; No homology to any previously reported sequences; 16893176, 7667876, 9482716.
  
     0.748
NIDE2405
Conserved protein of unknown function, TPR-like; Homologs of previously reported genes of unknown function; 14659697, 15361863, 16893176, 7667876, 9482716.
 
     0.658
NIDE3357
Putative Tol-Pal system protein YbgF; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.
 
     0.641
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.