Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gltDGlutamate synthase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (477 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 0.999
glnA
Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.980
fdsB
Formate dehydrogenase, beta subunit; Function of strongly homologous gene; enzyme.
 
 
 0.968
nuoF
NADH-quinone oxidoreductase, subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
 
 
 0.961
gdhA
Glutamate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.952
nuoF-2
NADH-quinone oxidoreductase, subunit F; Function of homologous gene experimentally demonstrated in an other organism; carrier.
 
 
 0.950
glmS
Glutamine--fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.918
putA
Bifunctional protein PutA; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family.
   
 0.917
carB
Carbamoyl-phosphate synthase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarB family.
  
 
 0.916
fdsA
Formate dehydrogenase, alpha subunit; Function of strongly homologous gene; enzyme.
    
 0.911
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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