Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE3387Sigma-54 dependent transcriptional regulator; Function of strongly homologous gene; regulator. (458 aa)    
Predicted Functional Partners:
rpoN
RNA polymerase, sigma-54 (sigma N) factor; Function of homologous gene experimentally demonstrated in an other organism; factor.
 
   
 0.710
NIDE3386
Homologs of previously reported genes of unknown function.
       0.662
NIDE4272
Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
   0.455
NIDE2290
Two-component system, NtrC family, nitrogen regulation response regulator NtrX; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
  
0.454
NIDE1772
Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.451
NIDE1119
Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
   0.436
NIDE3244
Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.428
NIDE3284
Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 
 0.422
NIDE3385
Polyprenyl-diphosphate synthase; Function of strongly homologous gene; enzyme; Belongs to the FPP/GGPP synthase family.
       0.420
NIDE2283
Putative Sensor histidine kinase FleS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
   0.419
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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