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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE3403Conserved membrane protein of unknown function, MarC-related; Homologs of previously reported genes of unknown function; 8383113. (215 aa)    
Predicted Functional Partners:
cbpA
Curved DNA-binding protein CbpA; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...]
       0.738
NIDE3404
Conserved exported protein of unknown function, putative Periplasmic protein CpxP; Homologs of previously reported genes of unknown function; 10671468, 10708362, 11285215, 11830644, 12670966, 9473036.
       0.689
NIDE3405
Conserved exported protein of unknown function, contains PepSY domain; Homologs of previously reported genes of unknown function; 12589825, 15124630, 15583150, 7674922.
       0.595
mscS
Small-conductance mechanosensitive channel; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
    0.555
NIDE3262
Putative Small-conductance mechanosensitive channel with cAMP-binding domain (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
    0.463
NIDE3947
Putative Small-conductance mechanosensitive channel MscS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
    0.454
NIDE3401
Putative ABC-type sugar transport system, ATPase component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the ABC transporter superfamily.
       0.419
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.