Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hddAD-glycero-D-manno-heptose 7-phosphate kinase; Function of strongly homologous gene; enzyme. (342 aa)    
Predicted Functional Partners:
gmhA
Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily.
 
 0.990
NIDE3423
Putative D-glycero-D-manno-heptose 1-phosphate guanosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 0.953
NIDE2328
Putative Galactokinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 
0.924
rfaF/gmhB
Heptosyltransferase II; Function of strongly homologous gene; enzyme.
  
 0.868
NIDE3422
Glycosyltransferase, family 2; Function of strongly homologous gene; enzyme.
       0.781
NIDE3424
Protein of unknown function; No homology to any previously reported sequences.
       0.773
NIDE2329
Putative Nucleotidyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 0.700
NIDE2327
Putative UDP-glucose 4-epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
    0.626
NIDE2331
Conserved protein of unknown function, Fe-S oxidoreductase; Homologs of previously reported genes of unknown function; 11222759, 11882645, 14633981, 14704425.
 
     0.535
NIDE3426
Conserved protein of unknown function, putative Methyltransferase; Homologs of previously reported genes of unknown function.
       0.522
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (14%) [HD]