Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
pilA2Type IV pilin PilA; Function of homologous gene experimentally demonstrated in an other organism; structure. (175 aa)    
Predicted Functional Partners:
pilC
Type IV pilus biogenesis protein PilC; Function of strongly homologous gene; transporter.
 
  
 0.977
pilA
Type IV pilin PilA; Function of homologous gene experimentally demonstrated in an other organism; structure.
 
  
0.946
gspF
General secretion pathway protein F; Function of strongly homologous gene; transporter.
 
  
 0.860
pilR
Transcriptional regulatory protein pilR; Function of strongly homologous gene; regulator.
      
 0.795
pilM
Type IV pilus biogenesis protein PilM; Function of strongly homologous gene; structure.
 
  
 0.791
pilD
Type IV pilus prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.771
gspE
General secretion pathway protein E; Function of strongly homologous gene; transporter.
 
 
 0.762
gspE2
General secretion pathway protein E, contains GAF domain; Function of strongly homologous gene; transporter.
 
 
 0.754
NIDE1352
Putative Type IV pili biogenesis protein PilQ; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.
 
  
 0.749
pilT1
Twitching mobility protein PilT; Function of homologous gene experimentally demonstrated in an other organism; structure.
 
   
 0.748
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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