STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Coexpression
Experiments
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[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (404 aa)    
Predicted Functional Partners:
xfp
D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; Function of strongly homologous gene; enzyme.
  
 0.972
NIDE3866
Putative Acyl-CoA synthetase (NDP forming); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 0.921
acyP
Acylphosphatase; Function of strongly homologous gene; enzyme.
     
 0.916
acsA
Acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
     
 0.914
acsA-2
Acetyl-CoA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.914
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
     
 0.704
NIDE3903
Alpha-glucan phosphorylase; Function of strongly homologous gene; enzyme.
     
 0.698
glgA
Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
      
 0.671
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
  
 0.594
NIDE3514
Conserved protein of unknown function, putative HAD-like hydrolase; Homologs of previously reported genes of unknown function.
       0.572
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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