Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE3521Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (677 aa)    
Predicted Functional Partners:
NIDE3520
Sigma-54 dependent response regulator; Function of strongly homologous gene; regulator.
 
 
   0.842
NIDE2021
Putative Histidine kinase, contains GAF domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 
 0.797
NIDE2070
Protein of unknown function, putative Response regulator with PAS domain S-box; No homology to any previously reported sequences; 14982921, 15009198, 16176121, 18076326, 7699720, 9301332, 9382818.
 
 
 
 0.797
NIDE2651
Putative Response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
   0.791
NIDE3585
Putative Response regulator, CheY-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
 
   0.776
NIDE3940
Putative Response regulator, CheY-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
 
   0.770
NIDE4086
Putative Response regulator, CheY-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
     0.768
NIDE3536
Putative Response regulator, CheY-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
 
   0.767
NIDE1763
Response regulator, CheY like; Function of strongly homologous gene; regulator.
  
 
   0.763
NIDE0545
Protein of unknown function, S-box protein; No homology to any previously reported sequences; 15009198, 9301332.
 
 
 
 0.750
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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