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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdtCMultidrug efflux system, subunit C; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1033 aa)    
Predicted Functional Partners:
mdtA
Multidrug efflux system, subunit A; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
   0.967
mdtB
Multidrug efflux system, subunit B; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
    
0.792
NIDE3530
Protein of unknown function; No homology to any previously reported sequences.
       0.773
rlmN
Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
      
 0.750
macB
ABC transporter, ATPase component, putative Macrolide export ATP-binding protein; Function of strongly homologous gene; enzyme.
 
    
 0.743
infA
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
      
 0.740
NIDE1686
Putative Membrane-fusion protein of multidrug efflux transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   0.695
NIDE3531
Transcriptional regulator, LysR family; Function of strongly homologous gene; regulator; Belongs to the LysR transcriptional regulatory family.
       0.664
cspA
Cold shock protein CspA; Function of homologous gene experimentally demonstrated in an other organism; factor.
      
 0.659
NIDE2964
Multidrug efflux transporter, membrane fusion protein; Function of strongly homologous gene; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   0.616
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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