Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
mdtAMultidrug efflux system, subunit A; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (412 aa)    
Predicted Functional Partners:
mdtB
Multidrug efflux system, subunit B; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
   0.968
mdtC
Multidrug efflux system, subunit C; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
   0.966
NIDE2965
Multidrug efflux transporter; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
   0.780
NIDE3530
Protein of unknown function; No homology to any previously reported sequences.
       0.773
NIDE1685
Putative Outer membrane protein TolC precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
  0.729
ttgB
RND efflux system, multidrug resistance protein; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
   0.720
NIDE3915
Putative Outer membrane efflux protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
  0.711
NIDE2718
Putative Outer membrane efflux protein precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
  0.707
NIDE3324
Efflux transporter, outer membrane factor lipoprotein; Function of strongly homologous gene; transporter.
  
   0.707
NIDE3198
Putative Outer membrane efflux protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
  0.694
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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