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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adaMethylated-DNA-[protein]-cysteine S-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (362 aa)    
Predicted Functional Partners:
rpoD
RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   0.834
rpoD-2
RNA polymerase sigma factor RpoD (Sigma-70); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
   0.834
rpoS
RNA polymerase, sigma S (sigma 38) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   0.834
rpoH
RNA polymerase, sigma 32 (sigma H) factor; Function of homologous gene experimentally demonstrated in an other organism; factor.
  
   0.834
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.600
mgtE
Magnesium transporter MgtE; Acts as a magnesium transporter.
      0.595
alkA
DNA-3-methyladenine glycosylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.585
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.564
NIDE2734
Putative Competence protein ComEC/Rec2 related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.544
cinA
CinA-like protein; Function of strongly homologous gene; cell process; Belongs to the CinA family.
     
 0.535
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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