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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rarAReplication-associated recombination protein A; Function of homologous gene experimentally demonstrated in an other organism; cell process. (429 aa)    
Predicted Functional Partners:
recQ
ATP-dependent DNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.865
NIDE3552
Exported protein of unknown function; No homology to any previously reported sequences.
       0.677
nadE
NAD(+) synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
    0.632
NIDE3554
Putative 3-oxoadipate enol-lactonase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.612
ftsK
DNA translocase FtsK; Function of strongly homologous gene; enzyme.
 
  
 0.601
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.506
NIDE0784
Conserved protein of unknown function, putative Peptidase; Homologs of previously reported genes of unknown function; 12711393, 1907934, 7845208, 8439290, 9070434.
 
     0.499
cinA
CinA-like protein; Function of strongly homologous gene; cell process; Belongs to the CinA family.
     
 0.455
mug
G:T/U mismatch-specific DNA glycosylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
    0.443
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.440
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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