close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE3564Protein of unknown function, contains von Willebrand factor; No homology to any previously reported sequences; 8440408, 9759493. (1011 aa)    
Predicted Functional Partners:
NIDE3569
Putative Regulatory protein, cbbQ/nirQ/norQ/gpvN family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
  
 0.867
NIDE3563
Protein of unknown function; No homology to any previously reported sequences.
       0.719
NIDE2577
Conserved membrane protein of unknown function, NnrS family; Homologs of previously reported genes of unknown function; 12618453.
 
    0.675
NIDE3565
Putative Ferredoxin-thioredoxin reductase, catalytic subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.625
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
       0.576
NIDE3566
Putative Peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.529
ATPase
ATPase, AAA family; Function of strongly homologous gene; enzyme.
  
  
 0.434
NIDE2038
Conserved protein of unknown function, putative AAA-5 ATPase; Homologs of previously reported genes of unknown function; 9927482.
  
  
 0.434
rlp
Ribulose bisphosphate carboxylase-like protein (RuBisCO type IV-like protein); Function of strongly homologous gene; enzyme.
 
   
 0.428
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (32%) [HD]