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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dcd2'-deoxycytidine 5'-triphosphate deaminase; Function of strongly homologous gene; enzyme. (383 aa)    
Predicted Functional Partners:
pyrG
CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
 
 0.926
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.926
NIDE3576
Membrane protein of unknown function; No homology to any previously reported sequences.
       0.826
kamA
L-lysine 2,3-aminomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.825
NIDE3579
Homologs of previously reported genes of unknown function.
       0.661
NIDE3577
Glycosyl transferase, family 2; Function of strongly homologous gene; enzyme.
  
    0.656
NIDE2576
Exported protein of unknown function; No homology to any previously reported sequences; 9463374.
 
   
 0.624
rfbD
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
   
    0.561
NIDE4374
Putative dTDP-4-dehydrorhamnose reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
    0.561
NIDE0121
Homologs of previously reported genes of unknown function.
  
     0.525
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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