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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE3591Putative Penicillin-binding protein 1B; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (767 aa)    
Predicted Functional Partners:
mrcA
Penicillin-binding protein 1A; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 
0.919
NIDE3590
Protein of unknown function DUF583; No homology to any previously reported sequences.
       0.685
murF
UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
   
 0.667
ftsW
Cell division protein FtsW; Function of homologous gene experimentally demonstrated in an other organism; cell process; Belongs to the SEDS family.
  
   
 0.653
mrdB
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
   
 0.615
murC
UDP-N-acetylmuramate-L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
   
 0.586
NIDE3065
Putative Murein hydrolase EnvC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process.
  
     0.584
NIDE3714
Conserved protein of unknown function, putative Peptidase M23B; Homologs of previously reported genes of unknown function.
  
   
 0.550
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
   
 0.515
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
   
 0.513
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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