Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
fkpAPeptidylprolyl isomerase, FKBP-type; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (225 aa)    
Predicted Functional Partners:
NIDE0867
Putative Surface antigen D15; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.
   
 
 0.761
NIDE3044
Putative Outer membrane protein assembly factor YaeT precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
   
 
 0.761
infA
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
   
   0.744
NIDE0556
Putative long-chain fatty acid outer membrane transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
    
 
 0.736
NIDE3592
Putative Porin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
    
 
 0.736
nirK
Copper-containing nitrite reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.732
lysC
Aspartokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family.
    
   0.727
NIDE2282
Protein of unknown function, TPR-like; No homology to any previously reported sequences; 14659697, 1882418, 7667876, 9482716.
   
 
 0.654
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
 
 
    0.642
NIDE2940
Homologs of previously reported genes of unknown function.
  
 
 0.642
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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