Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NIDE3621Exported protein of unknown function, putative Outer membrane protein; No homology to any previously reported sequences. (213 aa)    
Predicted Functional Partners:
NIDE0905
Protein of unknown function, putative Cytochrome c; No homology to any previously reported sequences; 3881803.
  
    0.708
qcrB
Quinol-cytochrome c reductase, fused cytochrome b/c subunit; Function of strongly homologous gene; carrier.
  
    0.708
NIDE1853
Putative Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
 0.624
NIDE0147
Putative Polyphosphate kinase 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
    0.570
NIDE3880
Conserved protein of unknown function, putative Polyphosphate kinase; Homologs of previously reported genes of unknown function; 12486232.
   
    0.570
NIDE3617
Homologs of previously reported genes of unknown function.
       0.461
NIDE3618
Putative Oxidoreductase with FAD/NAD(P)-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.461
NIDE3619
Homologs of previously reported genes of unknown function.
       0.461
NIDE3620
Putative Acetyltransferase, GNAT family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.461
NIDE3622
Putative Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
     
 0.422
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.