STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sigKRNA polymerase sigma factor SigK (Sigma-K); Function of strongly homologous gene; factor; Belongs to the sigma-70 factor family. ECF subfamily. (198 aa)    
Predicted Functional Partners:
NIDE3684
Conserved protein of unknown function, possible Anti-sigma-K factor; Homologs of previously reported genes of unknown function; 9573603.
 
 
 0.928
NIDE4245
Putative RNA polymerase sigma-E factor (Sigma-24); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.757
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.599
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.599
NIDE2175
Putative RNA polymerase sigma factor FecI (sigma-19); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.577
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.509
NIDE1746
Homologs of previously reported genes of unknown function.
 
 
 
 0.484
glbN
Hemoglobin-like protein HbN (modular protein); Function of strongly homologous gene; carrier.
       0.476
NIDE3526
Putative RNA polymerase sigma factor FecI (sigma-19); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.455
NIDE3687
Protein of unknown function; No homology to any previously reported sequences.
       0.440
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.