Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NIDE3701Homologs of previously reported genes of unknown function. (346 aa)    
Predicted Functional Partners:
NIDE3699
Putative Methyltransferase, UbiE-family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     0.948
NIDE3709
Putative Arsenite S-adenosylmethyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.891
NIDE3579
Homologs of previously reported genes of unknown function.
 
     0.785
NIDE0159
4-carboxymuconolactone decarboxylase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
    0.777
NIDE3702
Putative Inorganic phosphate transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
       0.773
NIDE3577
Glycosyl transferase, family 2; Function of strongly homologous gene; enzyme.
 
     0.764
NIDE3700
Putative Transcriptional regulator, ArsR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
       0.608
NIDE2793
Conserved protein of unknown function, putative Alkylhydroperoxidase AhpD; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
    0.582
NIDE3703
Homologs of previously reported genes of unknown function.
       0.487
NIDE1145
Conserved membrane protein of unknown function, DedA family; Homologs of previously reported genes of unknown function.
 
   
 0.463
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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