Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aoxBArsenite oxidase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (820 aa)    
Predicted Functional Partners:
aoxA
Arsenite oxidase, small subunit; Function of strongly homologous gene; enzyme.
 
  
 0.997
NIDE4261
Putative Formate hydrogenlyase, large subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.926
mgtA
Magnesium-transporting ATPase, P-type; Function of homologous gene experimentally demonstrated in an other organism; transporter.
      
 0.795
NIDE3706
Protein of unknown function; No homology to any previously reported sequences.
       0.773
fdsG
Formate dehydrogenase, gamma subunit; Function of strongly homologous gene; enzyme.
 
 
 0.769
nuoE
NADH-quinone oxidoreductase, subunit E; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.738
cbiX
Sirohydrochlorin cobaltochelatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.713
fdsB
Formate dehydrogenase, beta subunit; Function of strongly homologous gene; enzyme.
 
 
 0.679
NIDE1242
Putative [2Fe-2S] ferredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
  
 
 0.664
NIDE2772
Ferredoxin, 2Fe-2S; Function of strongly homologous gene; carrier.
  
 
 0.664
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (14%) [HD]