Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
arsCArsenate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (138 aa)    
Predicted Functional Partners:
NIDE3708
Putative Arsenite resistance protein ArsB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
 0.981
arsR
Arsenical resistance operon repressor; Function of homologous gene experimentally demonstrated in an other organism; regulator.
 
  
 0.918
nikR
Nickel-responsive regulator; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family.
      
 0.800
aclB
ATP-citrate lyase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.778
NIDE3709
Putative Arsenite S-adenosylmethyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
      0.735
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
 
      0.657
trxB
Thioredoxin-disulfide reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.518
trxC
Thioredoxin; Function of homologous gene experimentally demonstrated in an other organism; carrier.
  
 
 0.450
trxA
Thioredoxin; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the thioredoxin family.
  
 
 0.448
trxA-2
Thioredoxin; Function of strongly homologous gene; carrier; Belongs to the thioredoxin family.
  
 
 0.448
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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