close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE3708Putative Arsenite resistance protein ArsB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (353 aa)    
Predicted Functional Partners:
arsC
Arsenate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 0.981
radA
DNA recombination protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
     
 0.781
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
      
 0.691
arsR
Arsenical resistance operon repressor; Function of homologous gene experimentally demonstrated in an other organism; regulator.
  
  
 0.595
NIDE3709
Putative Arsenite S-adenosylmethyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.587
NIDE0472
Putative Low molecular weight protein-tyrosine-phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
  
 0.532
wzb
Low molecular weight protein-tyrosine-phosphatase Wzb; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
  
 0.532
aroF-2
Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).
 
      0.422
glnS
Glutaminyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
      0.421
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.