Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
arsRArsenical resistance operon repressor; Function of homologous gene experimentally demonstrated in an other organism; regulator. (111 aa)    
Predicted Functional Partners:
arsC
Arsenate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
 
  
 0.918
NIDE3709
Putative Arsenite S-adenosylmethyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.843
merP
Periplasmic mercury ion binding protein; Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
     
 0.832
merT
Mercury ion transport protein; Function of strongly homologous gene; transporter.
  
  
 0.805
nikR
Nickel-responsive regulator; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family.
      
 0.782
zitB
Zinc transporter ZitB; Function of homologous gene experimentally demonstrated in an other organism; transporter.
     
 0.779
aoxA
Arsenite oxidase, small subunit; Function of strongly homologous gene; enzyme.
      
 0.767
msrB
Methionine sulfoxide reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.739
phoB
Phosphate regulon transcriptional regulator PhoB; Function of strongly homologous gene; regulator.
      
 0.737
rpoN
RNA polymerase, sigma-54 (sigma N) factor; Function of homologous gene experimentally demonstrated in an other organism; factor.
      
 0.642
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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