Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hflKFtsH protease activity modulator HflK; HflC and HflK could encode or regulate a protease. (345 aa)    
Predicted Functional Partners:
hflC
FtsH protease activity modulator HflC; HflC and HflK could regulate a protease.
   
 0.997
cutA
Divalent-cation tolerance protein CutA; Function of homologous gene experimentally demonstrated in an other organism; factor.
     
 0.765
fdsA
Formate dehydrogenase, alpha subunit; Function of strongly homologous gene; enzyme.
      
 0.756
ttgA
RND efflux system, membrane fusion protein; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
      
 0.756
hslV
Heat shock protein HslUV, peptidase component; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
   
  
 0.755
acrB
Acriflavin resistance protein acrB; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
      
 0.754
nuoCD
NADH-quinone oxidoreductase, subunits C and D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 
 0.752
degP
Serine protease Do; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.741
degP-2
Protease Do; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.741
hflB
Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.709
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.