STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cysC2Adenylyl-sulfate kinase; Function of strongly homologous gene; enzyme; Belongs to the APS kinase family. (179 aa)    
Predicted Functional Partners:
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 0.989
cysD
Sulfate adenylyltransferase, subunit 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.987
cysNC
Sulfate adenylyltransferase, subunit 1, and adenylylsulfate kinase (bifunctional enzyme); Function of strongly homologous gene; enzyme.
 
 
 0.984
cysC
Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate.
  
  
 
0.916
NIDE0407
Putative Sulfite reductase, contains SirA-like domain (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
  
 0.851
cysE
Serine O-acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.809
cysW
Sulfate/thiosulfate ABC transporter, permease protein CysW; Function of homologous gene experimentally demonstrated in an other organism; transporter.
  
  
 0.808
NIDE3770
Homologs of previously reported genes of unknown function.
       0.799
cysT
Sulfate/thiosulfate ABC transporter, permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
  
  
 0.778
nirA
Ferredoxin-nitrite reductase; Function of strongly homologous gene; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
  
 0.746
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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