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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE3773Putative ATP-dependent protease, La homolog; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (804 aa)    
Predicted Functional Partners:
cspB
Cold shock protein modulated with ribosomal subunit interface-like protein; Function of strongly homologous gene; factor.
       0.776
NIDE3771
Protein of unknown function; Doubtful CDS.
       0.752
NIDE3774
Putative Regulatory protein, FmdB family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
       0.729
NIDE3775
Putative Cytochrome c552; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
       0.680
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
 
     0.643
pncA
Nicotine deamidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.576
NIDE3770
Homologs of previously reported genes of unknown function.
  
    0.560
cysC2
Adenylyl-sulfate kinase; Function of strongly homologous gene; enzyme; Belongs to the APS kinase family.
       0.531
NIDE3778
Homologs of previously reported genes of unknown function.
       0.439
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
    0.428
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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