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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pncANicotine deamidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (193 aa)    
Predicted Functional Partners:
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
 
 0.999
rih
Inosine-uridine preferring nucleoside hydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.924
npdA
NAD-dependent deacetylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the sirtuin family. Class III subfamily.
  
 0.918
yjeF
Conserved protein of unknown function, putative Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydr [...]
  
    0.676
NIDE3775
Putative Cytochrome c552; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
       0.651
NIDE3774
Putative Regulatory protein, FmdB family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
       0.610
NIDE3778
Homologs of previously reported genes of unknown function.
  
    0.602
cspB
Cold shock protein modulated with ribosomal subunit interface-like protein; Function of strongly homologous gene; factor.
  
    0.601
NIDE3773
Putative ATP-dependent protease, La homolog; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.576
NIDE3771
Protein of unknown function; Doubtful CDS.
       0.561
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.